Description

1,1-Dimethoxy-3-(Trimethylsiloxy)-1,3-Butadiene CAS NO 61539-61-5 is a specialized silyl enol ether derivative, a versatile and highly reactive synthon in advanced organic synthesis. Its core value lies in its ability to act as a masked 1,3-dicarbonyl equivalent, facilitating efficient carbon-carbon bond formation and the construction of complex heterocyclic and carbocyclic frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to streamline synthetic routes and develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, including antibiotics, anti-inflammatory agents, and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides requiring specific heterocyclic structures.
• Fine Chemical Manufacturing: Serves as a critical reagent for creating flavors, fragrances, and specialty performance chemicals.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic chemistry, particularly in annulation and cycloaddition reactions.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors and advanced polymeric materials.

Basic Information

Product Name	1,1-Dimethoxy-3-(Trimethylsiloxy)-1,3-Butadiene
CAS No.	61539-61-5
Molecular Formula	C9H18O3Si
Molecular Weight	202.32 g/mol
Synonyms	1,1-Dimethoxy-3-(trimethylsilyloxy)-1,3-butadiene; 3-(Trimethylsiloxy)-1,1-dimethoxy-1,3-butadiene; Danishefsky's Diene; (E)-1-Methoxy-3-[(trimethylsilyl)oxy]-1,3-butadiene; 1,1-Dimethoxy-3-trimethylsiloxybuta-1,3-diene; TMS Danishefsky Diene; 1,1-Dimethoxy-3-(trimethylsilyloxy)buta-1,3-diene
EINECS	Contact for details

Quality Control

Our production of 1,1-Dimethoxy-3-(Trimethylsiloxy)-1,3-Butadiene adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by advanced analytical techniques including GC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize shelf-life and stability. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when opening to prevent hydrolysis and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.