Description

D-Glucofuranose Cyclic 1,2-3,5 Bis(Butylboronate)-6-Acetate is a specialized organoboron derivative of glucose, serving as a key chiral intermediate and protecting group reagent in advanced synthetic chemistry. Its primary value lies in enabling stereoselective synthesis and facilitating complex multi-step reactions, particularly in the construction of carbohydrate-based molecules and nucleosides. This high-purity compound is essential for research and development laboratories in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with precise stereochemistry.

Application

• Pharmaceutical Intermediate: Critical for the stereoselective synthesis of nucleoside analogues, antiviral agents, and other chiral active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Used as a protected building block for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Agrochemical Development: Employed in creating chiral ligands and intermediates for novel pesticides and herbicides with enhanced specificity.
• Fine Chemical Synthesis: Acts as a versatile chiral auxiliary or protecting group in multi-step organic synthesis for high-value specialty chemicals.
• Process Chemistry & Scale-up: Serves as a key reagent in developing robust and scalable manufacturing routes for complex molecules.
• Academic & Industrial R&D: A valuable tool for methodological development in asymmetric synthesis and organoboron chemistry.

Basic Information

Product Name	D-Glucofuranose Cyclic 1,2-3,5 Bis(Butylboronate)-6-Acetate
CAS No.	61501-06-2
Molecular Formula	C18H31BO8
Molecular Weight	386.25 g/mol
Synonyms	1,2:3,5-Di-O-butylboron-D-glucofuranose 6-acetate; D-Glucose cyclic 1,2:3,5-bis(butylboronate) 6-acetate; 6-O-Acetyl-1,2:3,5-di-O-butylboranyl-D-glucofuranose; D-Glucofuranose, cyclic 1,2:3,5-bis(butylboronate) 6-acetate; Glucose bis(butylboronate) acetate derivative; Butylboronic acid cyclic ester with D-glucose 6-acetate
EINECS	Contact for details

Quality Control

Our D-Glucofuranose Cyclic 1,2-3,5 Bis(Butylboronate)-6-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide full traceability and detailed Certificates of Analysis (COA) to support your quality assurance and regulatory documentation needs for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis of the boronate ester groups and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.