Description

Butanoic Acid, 4-Bromo-2,2-Dimethyl-, Ethyl Ester is a specialized brominated ester derivative valued for its role as a versatile synthetic intermediate in advanced organic synthesis. This compound is particularly significant for introducing the 4-bromo-2,2-dimethylbutanoyl moiety into target molecules, enabling the construction of complex chemical architectures. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing sterically hindered, bromine-functionalized side chains.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its specific structure can contribute to biological activity.
• Organic Synthesis Reagent: Serves as a versatile electrophile or coupling partner in various name reactions, including palladium-catalyzed cross-couplings and nucleophilic substitutions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, or organic electronic materials that require brominated ester functionalities.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex ester molecules with specific olfactory properties, subject to purity and regulatory approval.

Basic Information

Product Name	Butanoic Acid, 4-Bromo-2,2-Dimethyl-, Ethyl Ester
CAS No.	61404-40-8
Molecular Formula	C8H15BrO2
Molecular Weight	223.11 g/mol
Synonyms	Ethyl 4-Bromo-2,2-dimethylbutanoate; 4-Bromo-2,2-dimethylbutyric Acid Ethyl Ester; 2,2-Dimethyl-4-bromobutanoic Acid Ethyl Ester; Ethyl 4-Bromo-2,2-dimethylbutyrate; Butanoic acid, 4-bromo-2,2-dimethyl-, ethyl ester; 4-Bromo-2,2-dimethyl-butanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 4-Bromo-2,2-Dimethyl-, Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards where required, ensuring the material is suitable for use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.