Description

6-Chloro-2,3-Dihydro-1H-Indene-1-Carboxylic Acid Ethyl Ester is a high-purity, versatile indane derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized bicyclic structure, which provides a rigid scaffold for constructing complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its chlorinated indane core.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or polymers requiring specific rigid aromatic units.
• Chemical Biology Probes: Functionalized to create molecular probes for studying enzyme function or cellular processes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up services.

Basic Information

Item	Details
Product Name	6-Chloro-2,3-Dihydro-1H-Indene-1-Carboxylic Acid Ethyl Ester
CAS No.	61346-39-2
Molecular Formula	C12H13ClO2
Molecular Weight	224.68 g/mol
Synonyms	Ethyl 6-Chloro-2,3-dihydro-1H-indene-1-carboxylate; 6-Chloro-1-indanecarboxylic Acid Ethyl Ester; 6-Chloroindane-1-carboxylic Acid Ethyl Ester; 1-Carbethoxy-6-chloroindane; 6-Chloro-2,3-dihydro-1H-indene-1-carboxylic acid, ethyl ester; Ethyl 6-chloroindane-1-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2,3-Dihydro-1H-Indene-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and other relevant techniques to verify identity, purity, and conformity to agreed specifications. Our quality assurance protocols are designed to meet the stringent requirements of R&D and cGMP-oriented production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.