Description

Ethanone, 1-Cyclohexyl-2,2-Difluoro- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclohexyl ring and gem-difluoro motif adjacent to the carbonyl, makes it a valuable precursor for introducing lipophilic and electron-withdrawing characteristics into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated, lipophilic fragments that can modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides where the difluoroketone moiety can enhance biological activity and environmental persistence profiles.
• Advanced Material Precursor: Acts as a building block for specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorine-based properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for various fluorination reactions, carbonyl chemistry, and as a scaffold for constructing complex, fluorinated heterocycles.
• Chemical Research Standard: Provided as a high-purity reference material for analytical method development and spectroscopic studies in fluoroorganic chemistry.

Basic Information

Item	Details
Product Name	Ethanone, 1-Cyclohexyl-2,2-Difluoro- (9Ci)
CAS No.	61153-51-3
Molecular Formula	C8H12F2O
Molecular Weight	162.18 g/mol
Synonyms	1-Cyclohexyl-2,2-difluoroethanone; 2,2-Difluoro-1-cyclohexylethanone; Cyclohexyl difluoroacetyl ketone; Difluoro(cyclohexyl)methyl ketone; α,α-Difluorocyclohexyl methyl ketone; (Cyclohexyl)difluoroacetyl; 61153-51-3 (CAS)
EINECS	Contact for details

Quality Control

Our Ethanone, 1-Cyclohexyl-2,2-Difluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and GC-MS, NMR (1H, 19F, 13C) for structural confirmation and impurity profiling. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure it meets your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.