Description

(9S)-9-Deoxo-9-[[(4-Ethylphenyl)Sulfonyl]Amino]Erythromycin is a semi-synthetic derivative of the macrolide antibiotic erythromycin, specifically modified at the 9-position. This chemical modification is significant for altering the compound's biological activity, pharmacokinetic profile, and stability, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel antibacterial agents and for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of next-generation macrolide antibiotics with potentially improved efficacy or reduced resistance.
• Research & Development: Critical material for medicinal chemistry programs focused on modifying erythromycin's core structure to explore new therapeutic applications.
• Process Chemistry: Used in scaling up and optimizing synthetic routes for the production of experimental drug candidates.
• Biochemical Research: Serves as a tool compound in microbiological and pharmacological studies to investigate bacterial ribosome interactions.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related pharmaceutical substances.

Basic Information

Product Name	(9S)-9-Deoxo-9-[[(4-Ethylphenyl)Sulfonyl]Amino]Erythromycin
CAS No.	61089-01-8
Molecular Formula	C39H66N2O12S
Molecular Weight	786.99 g/mol
Synonyms	9-Deoxo-9-[(4-ethylphenyl)sulfonyl]aminoerythromycin; 9(S)-9-Deoxo-9-[(p-ethylphenyl)sulfonyl]aminoerythromycin; Erythromycin 9-[(4-ethylphenyl)sulfonyl]imine derivative; N-[(4-Ethylphenyl)sulfonyl]erythromycylamine; (9S)-9-Deoxo-9-[(4-ethylbenzenesulfonyl)amino]erythromycin; A-69334; Antibiotic A 69334.
EINECS	Contact for details

Quality Control

Our (9S)-9-Deoxo-9-[[(4-Ethylphenyl)Sulfonyl]Amino]Erythromycin is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support compliance with cGMP standards for pharmaceutical intermediates, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.