Description

(9S)-9-Deoxo-9-[[[4-[(1-Oxopropyl)Amino]Phenyl]Sulfonyl]Amino]Erythromycin is a semi-synthetic derivative of the macrolide antibiotic erythromycin, specifically engineered to enhance stability and target specificity. This compound is valued for its role as a key intermediate in the research and development of advanced antibacterial agents and novel therapeutic candidates. It is primarily sought by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on combating antibiotic resistance and developing next-generation treatments.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel macrolide antibiotics with improved pharmacokinetic profiles.
• Antibacterial Research: Used in biochemical and microbiological studies to investigate structure-activity relationships (SAR) against resistant bacterial strains.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients (APIs) targeting respiratory and skin infections.
• Academic & Institutional Research: A valuable reference standard and synthetic target for studies in medicinal chemistry and pharmacology.
• Preclinical Studies: Utilized in the formulation of test compounds for in vitro and in vivo efficacy and toxicity evaluations.

Basic Information

Product Name	(9S)-9-Deoxo-9-[[[4-[(1-Oxopropyl)Amino]Phenyl]Sulfonyl]Amino]Erythromycin
CAS No.	61066-21-5
Molecular Formula	C41H73N3O13S
Molecular Weight	848.11 g/mol
Synonyms	9-Deoxo-9a-[[[4-[(1-oxopropyl)amino]phenyl]sulfonyl]amino]erythromycin; Erythromycin 9-[[[4-[(1-Oxopropyl)Amino]Phenyl]Sulfonyl]Amino] Derivative; 9(S)-9-Deoxo-9-[[[4-[(1-Oxopropyl)Amino]Phenyl]Sulfonyl]Amino]Erythromycin; 9a-[[[4-[(1-Oxopropyl)amino]phenyl]sulfonyl]amino]-9-deoxoerythromycin; Erythromycin A, 9-deoxo-9-[[[4-[(1-oxopropyl)amino]phenyl]sulfonyl]amino]-; (9S)-9-Deoxo-9-[[[4-[(1-oxopropyl)amino]phenyl]sulfonyl]amino]erythromycin
EINECS	Contact for details

Quality Control

Our (9S)-9-Deoxo-9-[[[4-[(1-Oxopropyl)Amino]Phenyl]Sulfonyl]Amino]Erythromycin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.