Description

2-Phenyl-4'-Trifluoromethylacetophenone is a specialized aromatic ketone derivative characterized by its phenyl and trifluoromethylphenyl substituents. This compound serves as a versatile and valuable advanced pharmaceutical intermediate (API) and a key building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl moiety imparts desired biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for organic electronic materials and liquid crystal compounds due to its rigid, conjugated structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, carbonyl chemistry, and as a scaffold for creating libraries of compounds in medicinal chemistry.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	2-Phenyl-4'-Trifluoromethylacetophenone
CAS No.	61062-55-3
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	1-[4-(Trifluoromethyl)phenyl]-2-phenylethan-1-one; 2-Phenyl-1-[4-(trifluoromethyl)phenyl]ethanone; 4'-Trifluoromethyl-2-phenylacetophenone; 4-(Trifluoromethyl)desoxybenzoin; α-Phenyl-4'-(trifluoromethyl)acetophenone; Desoxybenzoin, 4'-trifluoromethyl-; Ethanone, 1-[4-(trifluoromethyl)phenyl]-2-phenyl-
EINECS	Contact for details

Quality Control

Our 2-Phenyl-4'-Trifluoromethylacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.