Description

2-Bromo-4-tert-Butyl-1-Chlorobenzene is a halogenated aromatic compound that serves as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents on a tert-butyl benzene ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research institutions and chemical manufacturers engaged in the development of pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and pesticides where the tert-butyl and halogen groups contribute to biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where its structure can tune electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine substituent.
• Chemical Research & Development: A standard reagent in R&D laboratories for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Item	Detail
Product Name	2-Bromo-4-tert-Butyl-1-Chlorobenzene
CAS No.	61024-95-1
Molecular Formula	C10H12BrCl
Molecular Weight	247.56 g/mol
Synonyms	1-Chloro-2-bromo-4-tert-butylbenzene; 4-tert-Butyl-1-chloro-2-bromobenzene; 2-Bromo-4-(tert-butyl)chlorobenzene; 2-Bromo-4-tert-butylchlorobenzene; 1-Bromo-2-chloro-5-tert-butylbenzene (alternative numbering); 4-(1,1-Dimethylethyl)-1-chloro-2-bromobenzene; 2-Bromo-4-(1,1-dimethylethyl)-1-chlorobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-tert-Butyl-1-Chlorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.