Description

25-Acetoxy-2-(β-D-Glucopyranosyloxy)-16α,20-Dihydroxycucurbita-1,5-Diene-3,11,22-Trione is a highly functionalized cucurbitane-type triterpenoid glycoside derivative, representing a key intermediate in the synthesis of complex bioactive natural products. This compound matters for its role as a sophisticated chemical building block in advanced pharmaceutical research and development, particularly for exploring novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on steroid-mimetic compounds, anti-inflammatory agents, and metabolic pathway modulators.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates with potential anti-diabetic, anti-inflammatory, or anti-cancer activities.
• Biochemical Research: Used as a reference standard or probe compound in metabolic studies and enzyme inhibition assays to investigate biological pathways.
• Natural Product Synthesis: A key chiral building block for the semi-synthesis or total synthesis of complex cucurbitacin analogs and other triterpenoid derivatives.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value target molecules in fine chemical manufacturing.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of triterpenoid glycosides.

Basic Information

Item	Detail
Product Name	25-Acetoxy-2-(β-D-Glucopyranosyloxy)-16α,20-Dihydroxycucurbita-1,5-Diene-3,11,22-Trione
CAS No.	61014-18-4
Molecular Formula	C38H54O13
Molecular Weight	718.83 g/mol
Synonyms	2β-(β-D-Glucopyranosyloxy)-16α,20-dihydroxy-25-acetoxycucurbita-1,5-diene-3,11,22-trione; Cucurbitacin IIb 2-O-β-D-glucopyranoside 25-acetate; 25-Acetylcucurbitacin F 2-O-β-D-glucoside; 25-Acetoxycucurbitacin F 2-O-β-glucoside; 25-O-Acetyl-2-O-β-D-glucopyranosylcucurbitacin F; (3β,16α,23E)-25-(Acetyloxy)-16,20-dihydroxy-9-methyl-19-norlanosta-1,5,23-triene-3,11,22-trione 3-(β-D-glucopyranoside)
EINECS	Contact for details

Quality Control

Our 25-Acetoxy-2-(β-D-Glucopyranosyloxy)-16α,20-Dihydroxycucurbita-1,5-Diene-3,11,22-Trione is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to ensure structural identity and high purity, suitable for research and development applications. Certificates of Analysis (COA) with full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.