Description

4'-Fluorobiphenyl-4-Carbaldehyde is a high-purity fluorinated aromatic aldehyde building block. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of both a biphenyl core and a formyl functional group. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and novel crop protection agents. Its specific structure makes it a critical precursor in medicinal chemistry and materials science applications.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and receptor antagonist research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated organic semiconductors and liquid crystal display (LCD) components.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Organic Ligand Synthesis: Utilized for preparing specialized ligands used in catalysis and coordination chemistry.
• Polymer & Resin Modifier: Incorporated into polymer chains to alter physical properties like thermal stability and solubility.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for exploring new synthetic methodologies.

Basic Information

Product Name	4'-Fluorobiphenyl-4-Carbaldehyde
CAS No.	60992-98-5
Molecular Formula	C₁₃H₉FO
Molecular Weight	200.21 g/mol
Synonyms	4-(4-Fluorophenyl)benzaldehyde; [1,1'-Biphenyl]-4-carboxaldehyde, 4'-fluoro-; 4'-Fluoro-4-biphenylcarboxaldehyde; 4-Formyl-4'-fluorobiphenyl; p-Fluorophenylbenzaldehyde; 4-(4-Fluorophenyl)benzenecarboxaldehyde; 4'-Fluorobiphenyl-4-aldehyde
EINECS	Contact for details

Quality Control

Our 4'-Fluorobiphenyl-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with global regulatory frameworks, and our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.