Description

4-Bromo-2-Chloro-1-Fluorobenzene is a high-purity halogenated benzene derivative, a key building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an indispensable intermediate for creating complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogen atoms contribute to biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic components in electronic display materials and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Polymer Monomer: Employed in the synthesis of specialty polymers with enhanced thermal stability or specific optical properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	4-Bromo-2-Chloro-1-Fluorobenzene
CAS No.	60811-21-4
Molecular Formula	C6H3BrClF
Molecular Weight	209.44 g/mol
Synonyms	1-Bromo-4-Chloro-2-Fluorobenzene; 2-Chloro-4-Bromofluorobenzene; 4-Bromo-2-chlorofluorobenzene; 2-Chloro-1-fluoro-4-bromobenzene; Benzene, 4-bromo-2-chloro-1-fluoro-; 4-Bromo-2-chloro-1-fluorobenzol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-1-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Standard Grade)
Purity (GC/HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.