Description

5-Fluoro-Benzofuran-3-One is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research institutions and industrial manufacturers engaged in the synthesis of novel active ingredients, where its unique fluorine-substituted benzofuranone scaffold enables the fine-tuning of biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in organic chemistry as a versatile fluorinated synthon for constructing complex heterocyclic frameworks.
• Life Science Reagents: Utilized in the development of biochemical probes, fluorescent tags, and other research tools.

Basic Information

Product Name	5-Fluoro-Benzofuran-3-One
CAS No.	60770-49-2
Molecular Formula	C8H5FO2
Molecular Weight	152.12 g/mol
Synonyms	5-Fluorobenzofuran-3-one; 5-Fluoro-3-benzofuranone; 5-Fluoro-1-benzofuran-3(2H)-one; 3H-Benzofuran-3-one, 5-fluoro-; 5-Fluorophthalide (common misnomer, structurally related); 5-Fluoroisobenzofuran-1(3H)-one (alternative numbering); 5-Fluoro-3-oxo-2,3-dihydrobenzofuran
EINECS	Contact for details

Quality Control

Our 5-Fluoro-Benzofuran-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.