Description

2-Trifluoromethylcycloheptanone is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group attached to a seven-membered cyclic ketone framework. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases, where the CF₃ group can enhance metabolic stability and lipophilicity.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl moiety to improve biological activity and environmental profile.
• Advanced Material Precursor: Serves as a building block for fluorinated polymers, liquid crystals, and specialty coatings, where the incorporation of fluorine atoms can alter surface energy and chemical resistance.
• Organic Synthesis Reagent: Employed in ring-expansion reactions, nucleophilic additions, and as a scaffold for constructing complex, stereodefined cyclic compounds in medicinal chemistry.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on understanding the stereoelectronic effects and reactivity of fluorinated alicyclic ketones.

Basic Information

Product Name	2-Trifluoromethylcycloheptanone
CAS No.	60719-13-3
Molecular Formula	C₈H₁₁F₃O
Molecular Weight	180.17 g/mol
Synonyms	2-(Trifluoromethyl)cycloheptan-1-one; 2-(Trifluoromethyl)cycloheptanone; Cycloheptanone, 2-(trifluoromethyl)-; 2-Trifluoromethyl-1-cycloheptanone; 1-Cycloheptanone, 2-(trifluoromethyl)-; α-Trifluoromethylcycloheptanone; 2-Trifluoromethylcycloheptan-1-one
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethylcycloheptanone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, GC analysis, and NMR spectroscopic confirmation (¹H, ¹³C, ¹⁹F) to verify identity and quality. Certificates of Analysis (COA) detailing all specifications are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.