Description

1-Cyclobutene-1-Carboxylicacid,3,4-Dimethyl-,Methylester,trans-(9Ci) is a specialized, high-purity organic ester building block with a defined stereochemistry. This compound matters as a critical chiral intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists working on novel active ingredients, particularly where the trans configuration of the cyclobutene ring is essential for biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel small-molecule drug candidates, especially in therapeutic areas requiring constrained ring systems.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can contribute to unique modes of action.
• Material Science Research: Serves as a monomer or precursor for developing specialized polymers with tailored thermal or optical properties.
• Organic Synthesis & Catalysis: A valuable building block in academic and industrial laboratories for methodological studies, including cycloaddition reactions and asymmetric catalysis.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex ester-based aroma chemicals, given its unique bicyclic structure.

Basic Information

Product Name	1-Cyclobutene-1-Carboxylicacid,3,4-Dimethyl-,Methylester,trans-(9Ci)
CAS No.	60697-53-2
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	trans-Methyl 3,4-dimethyl-1-cyclobutene-1-carboxylate; Methyl trans-3,4-dimethylcyclobut-1-ene-1-carboxylate; 3,4-Dimethyl-1-cyclobutene-1-carboxylic Acid Methyl Ester, trans-; (1R,2S)-rel-3,4-Dimethyl-1-cyclobutene-1-carboxylic Acid Methyl Ester; 1-Cyclobutene-1-carboxylic acid, 3,4-dimethyl-, methyl ester, (1R,2S)-rel-; 60697-53-2; trans-3,4-Dimethylcyclobut-1-ene-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Cyclobutene-1-Carboxylicacid,3,4-Dimethyl-,Methylester,trans-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including GC, HPLC, and NMR to verify specifications and confirm the critical trans stereochemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.