Description

2-Bromo-4-Chloroanisole is a halogenated anisole derivative, a versatile and high-purity organic intermediate essential for advanced chemical synthesis. Its value lies in its precise bromine and chlorine substitution pattern, which enables the controlled introduction of functional groups into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as API synthesis and material science research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the bromo-chloro-anisole structure acts as a core scaffold.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling carbon-carbon and carbon-heteroatom bond formation.
• Functional Dye & Pigment Intermediate: Employed in the development of complex dyes and pigments where halogen atoms are crucial for color fastness and specific light-absorption properties.
• Organic Synthesis & Process Chemistry: A valuable reagent for academic and industrial research in constructing complex polyfunctional aromatic and heteroaromatic systems.

Basic Information

Product Name	2-Bromo-4-Chloroanisole
CAS No.	60633-25-2
Molecular Formula	C7H6BrClO
Molecular Weight	221.48 g/mol
Synonyms	1-Bromo-2-chloro-4-methoxybenzene; 2-Bromo-4-chloro-1-methoxybenzene; 4-Chloro-2-bromoanisole; Benzene, 1-bromo-2-chloro-4-methoxy-; Anisole, 2-bromo-4-chloro-; 2-Bromo-4-chloromethoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloroanisole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity while monitoring for specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with global regulatory frameworks, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.