Description

6-Bromovanillin is a versatile halogenated derivative of vanillin, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the introduction of a bromine atom at the 6-position, which provides a reactive handle for further functionalization via cross-coupling reactions or nucleophilic substitution. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its modified phenolic structure.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Flavor and Fragrance Chemistry: Acts as an intermediate for synthesizing novel, complex aroma chemicals and flavor modifiers with unique sensory properties.
• Material Science Research: Employed in the development of advanced polymers, resins, and functional materials where a brominated aromatic moiety is required.
• Organic Synthesis Reagent: A valuable reagent for introducing the vanillin scaffold with a halogen substituent for further palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig couplings.

Basic Information

Product Name	6-Bromovanillin
CAS No.	60632-40-8
Molecular Formula	C8H7BrO3
Molecular Weight	231.05 g/mol
Synonyms	6-Bromo-4-hydroxy-3-methoxybenzaldehyde; 6-Bromovanillin; 3-Methoxy-6-bromo-4-hydroxybenzaldehyde; 4-Hydroxy-3-methoxy-6-bromobenzaldehyde; Vanillin, 6-bromo-; 6-BV; 6-Bromo-protocatechualdehyde methyl ether
EINECS	262-300-9

Quality Control

Our 6-Bromovanillin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	163 - 167 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.