Description

Boc-L-Phe-Chn2 is a protected amino acid derivative, specifically an N-Boc-protected phenylalanine nitrile, widely used as a crucial chiral building block in organic synthesis. Its primary value lies in providing a versatile and stereochemically defined intermediate for constructing complex peptides and other bioactive molecules. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in the development of novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid precursor in solid-phase and solution-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains.
• Proteomics Research: Used in biochemical research for studying protein structure-function relationships and developing peptide probes or substrates.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, including chiral ligands, catalysts, and advanced organic materials.
• Academic & R&D Laboratories: Fundamental building block for synthetic organic chemistry research, methodology development, and exploring new chemical entities.

Basic Information

Product Name	Boc-L-Phe-Chn2
CAS No.	60398-41-6
Molecular Formula	C₁₅H₂₀N₂O₂
Molecular Weight	260.33 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-phenylalanine nitrile; Boc-Phe-CN; (S)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropanenitrile; Boc-L-Phenylalanine cyanomethyl ester (common misnomer); N-Boc-L-phenylalaninenitrile; tert-Butyl (S)-(1-cyano-2-phenylethyl)carbamate; (S)-2-(Boc-amino)-3-phenylpropionitrile; L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, nitrile
EINECS	Contact for details

Quality Control

Our Boc-L-Phe-Chn2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP guidelines where applicable to support its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is strictly light-sensitive and must be protected from all light exposure to maintain stability. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.