Description

(2S)-2-(Bromomethyl)-1-Methyl-Pyrrolidine CAS NO 60365-88-0 is a high-purity chiral building block and key synthetic intermediate characterized by its bromomethyl functional group on a pyrrolidine scaffold. This compound matters for its critical role in facilitating stereoselective synthesis and molecular diversification in advanced pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the stereoselective synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to introduce functionalized pyrrolidine motifs into novel compounds.
• Agrochemical Synthesis: Serves as a building block for creating chiral pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological targets and pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	(2S)-2-(Bromomethyl)-1-Methyl-Pyrrolidine
CAS No.	60365-88-0
Molecular Formula	C7H14BrN
Molecular Weight	192.10 g/mol
Synonyms	(S)-2-(Bromomethyl)-1-methylpyrrolidine; 1-Methyl-2-(bromomethyl)pyrrolidine, (2S)-; (S)-1-Methyl-2-(bromomethyl)pyrrolidine; (2S)-1-Methyl-2-(bromomethyl)pyrrolidine; L-Proline, 2-(bromomethyl)-, N-methyl-; Pyrrolidine, 2-(bromomethyl)-1-methyl-, (2S)-; (S)-N-Methyl-2-(bromomethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (2S)-2-(Bromomethyl)-1-Methyl-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.