Description

Methanesulfonic Acid, Trifluoro-, 1-Methylpropyl Ester is a specialized fluorinated sulfonate ester, a key building block in advanced organic synthesis. This compound matters for its role as a versatile reagent and intermediate, enabling the introduction of the trifluoromethanesulfonyl group to create molecules with enhanced properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex fluorinated target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the triflate group acts as a superior leaving group in coupling reactions.
• Polymer & Materials Science: Employed as a monomer or modifying agent in the development of specialty polymers, including fluoropolymers with unique thermal and chemical resistance.
• Cross-Coupling Reactions: Acts as an effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) due to the reactivity of the triflate ester group.
• Ligand and Catalyst Preparation: Utilized in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Organic Electronics: Finds application in the research and development of materials for organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	Methanesulfonic Acid, Trifluoro-, 1-Methylpropyl Ester
CAS No.	60306-26-5
Molecular Formula	C6H9F3O3S
Molecular Weight	218.19 g/mol
Synonyms	1-Methylpropyl Trifluoromethanesulfonate; sec-Butyl Triflate; Trifluoromethanesulfonic Acid sec-Butyl Ester; 2-Butyl Trifluoromethanesulfonate; sec-Butyl Trifluoromethanesulfonate; Butan-2-yl Trifluoromethanesulfonate; Triflic Acid sec-Butyl Ester; 1-Methylpropyl Triflate
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, Trifluoro-, 1-Methylpropyl Ester is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its reactivity, store separately from strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.30 g/mL
Refractive Index (n20D)	~1.35

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.