Description

tert-Butyl 2-(tert-Butyl)-1-Hydrazinecarboxylate is a specialized, high-purity Boc-protected hydrazine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the tert-butyloxycarbonyl (Boc) protecting group to hydrazine functionalities, enabling precise control over reaction pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), heterocyclic compounds, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules, particularly in constructing hydrazide and hydrazone linkages found in various drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators where protected hydrazine moieties are required.
• Peptide Mimetics & Conjugate Chemistry: Facilitates the controlled incorporation of hydrazine units into peptide chains and bioconjugates for drug delivery and diagnostic applications.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, such as polyhydrazides, with specific thermal or mechanical properties.
• Research & Development: An essential reagent in academic and industrial labs for methodological development in synthetic organic chemistry.
• Chemical Derivatization: Employed to protect sensitive hydrazine groups during multi-step synthetic sequences, improving yield and selectivity.

Basic Information

Product Name	tert-Butyl 2-(tert-Butyl)-1-Hydrazinecarboxylate
CAS No.	60295-52-5
Molecular Formula	C9H20N2O2
Molecular Weight	188.27 g/mol
Synonyms	1-Boc-2-tert-butylhydrazine; tert-Butyl N-(tert-butylcarbamoyl)carbamate; 2-(tert-Butyl)-1-[(tert-butoxy)carbonyl]hydrazine; 1-(tert-Butoxycarbonyl)-2-(tert-butyl)hydrazine; Boc-NH-NH-tBu; N-Boc-N'-tert-butylhydrazine; Di-tert-butyl hydrazine-1,2-dicarboxylate (isomer); tert-Butyl hydrazine-1,2-dicarboxylate, 2-tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(tert-Butyl)-1-Hydrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.