Description

Cyclopropyl 2,4-Difluorophenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a cyclopropyl and a difluorophenyl moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms and cyclopropyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated organic compounds for advanced materials, such as liquid crystals or polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Cyclopropyl 2,4-Difluorophenyl Ketone
CAS No.	60131-34-2
Molecular Formula	C10H8F2O
Molecular Weight	182.17 g/mol
Synonyms	2,4-Difluorocyclopropyl phenyl ketone; 1-Cyclopropyl-2,4-difluorophenylmethanone; (2,4-Difluorophenyl)cyclopropylmethanone; Cyclopropyl(2,4-difluorophenyl)methanone; 60131-34-2; 2,4-Difluorobenzoylcyclopropane
EINECS	Contact for details

Quality Control

Our Cyclopropyl 2,4-Difluorophenyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.