Description

Pentafluorophenyl Trifluoromethanesulfonate is a highly reactive and versatile fluorinated sulfonate ester, widely recognized as a superior reagent for introducing the pentafluorophenyl group. This compound matters for its exceptional leaving group ability, enabling efficient derivatization and functionalization reactions under mild conditions. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing complex molecules and specialty polymers.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the preparation of active pharmaceutical ingredients (APIs), particularly in nucleophilic aromatic substitution reactions.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require fluorinated aromatic components for enhanced bioactivity and stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty fluoropolymers with unique thermal, chemical, and surface properties.
• Ligand & Catalyst Preparation: Employed to synthesize sophisticated ligands and organometallic catalysts used in asymmetric synthesis and coupling reactions.
• Analytical Chemistry: Acts as a derivatization agent for gas chromatography (GC) or mass spectrometry (MS) to improve the detection and analysis of sensitive compounds.
• Organic Synthesis Reagent: A powerful tool for forming carbon-heteroatom and carbon-carbon bonds in complex multi-step synthetic pathways.

Basic Information

Product Name	Pentafluorophenyl Trifluoromethanesulfonate
CAS No.	60129-85-3
Molecular Formula	C7HF8O3S
Molecular Weight	296.13 g/mol
Synonyms	Pentafluorophenyl Triflate; PFP-Triflate; Trifluoromethanesulfonic Acid Pentafluorophenyl Ester; Perfluorophenyl Trifluoromethanesulfonate; 2,3,4,5,6-Pentafluorophenyl Triflate; NSC 405124; Pentafluorophenyl Trifluoromethylsulfonate
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.