Description

(4-Bromophenyl)(Cyclopropyl)Methanone is a high-purity organic building block featuring a brominated aromatic ketone core with a cyclopropyl substituent. This compound is valued for its unique structural motif, which serves as a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry for lead optimization and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the cyclopropyl group's bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(4-Bromophenyl)(Cyclopropyl)Methanone
CAS No.	6952-89-2
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	4-Bromophenyl cyclopropyl ketone; Cyclopropyl 4-bromophenyl ketone; 1-(4-Bromophenyl)-1-cyclopropylmethanone; p-Bromophenyl cyclopropyl ketone; 4'-Bromopropiophenone, cyclopropyl-; (4-Bromophenyl)cyclopropylmethanone; 4-Bromobenzoylcyclopropane
EINECS	Contact for details

Quality Control

Our (4-Bromophenyl)(Cyclopropyl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.