Description

5-Amino-2-Bromo-Benzoic Acid Methyl Ester is a high-purity, multi-functional chemical intermediate of significant commercial importance. Its molecular structure, featuring both amino and bromo substituents on a benzoic acid ester core, makes it a versatile building block for synthesizing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Dye and Pigment Manufacturing: Serves as a foundational component for creating complex organic dyes, pigments, and colorants due to its reactive amino and bromo groups.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers where specific electronic properties are required.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl and heterocyclic systems in medicinal chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up processes.

Basic Information

Product Name	5-Amino-2-Bromo-Benzoic Acid Methyl Ester
CAS No.	6942-37-6
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	Methyl 5-Amino-2-Bromobenzoate; 2-Bromo-5-Aminobenzoic Acid Methyl Ester; Benzoic acid, 5-amino-2-bromo-, methyl ester; Methyl 2-Bromo-5-aminobenzoate; 5-Amino-2-Bromobenzoic Acid Methyl Ester; 2-Bromo-5-Aminomethyl Benzoate; Methyl 5-Amino-2-Bromo-Benzoate
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Bromo-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.