Description

1-(Bromomethyl)-4-Fluoro-1-Naphthalene is a versatile halogenated naphthalene derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a fluorine substituent, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated organic semiconductors and charge-transport materials for electronic displays.
• Polymer & Resin Modification: Employed to introduce functional naphthalene units into polymer backbones, altering thermal and optical properties.
• Cross-Coupling Reactions: The bromomethyl group acts as an effective handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Fluorine Chemistry Research: A valuable substrate for studying the effects of fluorine substitution on aromatic systems and subsequent reaction pathways.

Basic Information

Product Name	1-(Bromomethyl)-4-Fluoro-1-Naphthalene
CAS No.	6905-05-1
Molecular Formula	C₁₁H₈BrF
Molecular Weight	239.09 g/mol
Synonyms	4-Fluoro-1-(bromomethyl)naphthalene; 1-(Bromomethyl)-4-fluoronaphthalene; 4-Fluoro-1-naphthalenemethyl bromide; 1-Bromomethyl-4-fluoronaphthalene; (4-Fluoronaphthalen-1-yl)methyl bromide; α-Bromo-4-fluoro-1-naphthalenemethane; 6905-05-1; 4-Fluoro-1-naphthylmethyl bromide
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-4-Fluoro-1-Naphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.