Description

(3S,3Ar,4S,6E,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3,6,10-Trimethylcyclodeca[B]Furan-2-One is a complex sesquiterpene lactone derivative with a defined stereochemistry, valued for its unique structural framework. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive natural product analogs. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity, structurally sophisticated intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including anti-inflammatory and anticancer compounds.
• Agrochemical Synthesis: Used in the development of advanced, biologically active ingredients for crop protection products.
• Natural Product Analog Synthesis: Serves as a core scaffold for synthesizing analogs of complex sesquiterpenoids for biological activity studies.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new stereoselective catalytic processes.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex, high-value aroma chemicals due to its terpenoid backbone.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in total synthesis and medicinal chemistry.

Basic Information

Product Name	(3S,3Ar,4S,6E,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3,6,10-Trimethylcyclodeca[B]Furan-2-One
CAS No.	6895-46-1
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	4-Hydroxy-3,6,10-trimethylcyclodeca[b]furan-2(3H)-one; (3S,3aR,4S,6E,10E,11aR)-2,3,3a,4,5,8,9,11a-Octahydro-4-hydroxy-3,6,10-trimethylcyclodeca[b]furan-2-one; A sesquiterpene lactone derivative; Cyclodeca[b]furan-2-one, 2,3,3a,4,5,8,9,11a-octahydro-4-hydroxy-3,6,10-trimethyl-, (3S,3aR,4S,6E,10E,11aR)-; CAS 6895-46-1
EINECS	Contact for details

Quality Control

Our (3S,3Ar,4S,6E,10E,11Ar)-2,3,3A,4,5,8,9,11A-Octahydro-4-Hydroxy-3,6,10-Trimethylcyclodeca[B]Furan-2-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.