Description

Methyl Diazoacetate is a versatile and highly reactive organic compound primarily used as a key building block in organic synthesis. Its value lies in its ability to serve as a precursor to cyclopropanes and other strained ring systems, as well as a source of carbene equivalents for C-H insertion and cyclopropanation reactions. This makes it an essential reagent for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane rings or other complex heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactivity enables the creation of novel, potent bioactive molecules.
• Organic Synthesis Reagent: Employed in laboratory-scale and pilot-scale organic reactions, including cyclopropanation, homologation, and C-H functionalization.
• Polymer & Materials Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Methyl Diazoacetate
CAS No.	6832-16-2
Molecular Formula	C3H4N2O2
Molecular Weight	100.08 g/mol
Synonyms	Diazoacetic Acid Methyl Ester; Methyl 2-Diazoacetate; Acetic Acid, 2-Diazo-, Methyl Ester; Methyl Glyoxylate Diazonium Betaine; Methyl Diazomalonate (common misnomer); Methyl Diazooacetate; NSC 406019
EINECS	229-914-3

Quality Control

Our Methyl Diazoacetate is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including purity assay and impurity profiling. A Certificate of Analysis (COA) detailing specific results for identity, purity, and relevant physical parameters is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place, away from heat sources and incompatible materials. Due to its light-sensitive and potentially unstable diazo nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Always allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Clear, yellow to orange liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.