Description

3α,7α,12α-Triacetoxy-5β-Cholan-24-Oic Acid Methyl Ester is a key cholic acid derivative and a crucial synthetic intermediate in the production of bile acids and their analogs. This compound matters for its role as a versatile building block in pharmaceutical research and development, enabling the synthesis of complex therapeutic agents. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for developing new drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of ursodeoxycholic acid (UDCA), chenodeoxycholic acid (CDCA), and other therapeutic bile acids.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Research: Serves as a substrate or intermediate in metabolic pathway studies and enzymatic research related to cholesterol and bile acid metabolism.
• Fine Chemical Synthesis: Employed as a specialized building block for creating novel steroid-based compounds with potential biological activity.
• API Development: Integral to the research and process development for Active Pharmaceutical Ingredients (APIs) targeting liver and metabolic disorders.

Basic Information

Product Name	3α,7α,12α-Triacetoxy-5β-Cholan-24-Oic Acid Methyl Ester
CAS No.	6818-44-6
Molecular Formula	C₂₉H₄₆O₇
Molecular Weight	506.68 g/mol
Synonyms	Methyl 3α,7α,12α-triacetoxy-5β-cholan-24-oate; Methyl 3α,7α,12α-triacetoxy-5β-cholanate; Cholan-24-oic acid, 3,7,12-triacetoxy-, methyl ester, (3α,5β,7α,12α)-; Methyl triacetoxycholanate; Triacetyl methyl cholate; 5β-Cholan-24-oic acid, 3α,7α,12α-triacetoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 3α,7α,12α-Triacetoxy-5β-Cholan-24-Oic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets stringent specifications for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.