Description

Diethyl Isopropylidenemalonate is a versatile malonate ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive methylene group and ester functionalities, enabling efficient carbon-carbon bond formation and ring-closure reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in constructing heterocyclic frameworks found in modern pesticides, herbicides, and fungicides.
• Fine Chemical Production: Serves as a starting material for synthesizing flavors, fragrances, and specialty polymers.
• Academic & R&D: Employed in research laboratories for methodological development and exploring new synthetic pathways in organic chemistry.
• Chemical Synthesis: Utilized in Knoevenagel condensations, Michael additions, and the preparation of carboxylic acids and ketones via hydrolysis and decarboxylation.

Basic Information

Item	Detail
Product Name	Diethyl Isopropylidenemalonate
CAS No.	6802-75-1
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	Diethyl 2-(propan-2-ylidene)malonate; Isopropylidenemalonic Acid Diethyl Ester; Propanedioic acid, 2-(1-methylethylidene)-, diethyl ester; Diethyl isopropylidenemalonate; Diethyl (1-methylethylidene)malonate; DEPM; Malonic acid, isopropylidene-, diethyl ester
EINECS	229-874-5

Quality Control

Our Diethyl Isopropylidenemalonate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (IR, NMR), to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The product is sensitive to moisture and prolonged exposure to light.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.440 - 1.445
Density (20°C)	1.02 - 1.06 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.