Description

4-Chloro-2-Fluoroiodobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of chlorine, fluorine, and iodine substituents makes it a versatile and highly reactive intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce halogenated aryl groups into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic rings for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogen pattern can influence binding to biological targets.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, leveraging the iodine atom for selective functionalization.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring new synthetic routes and creating compound libraries for screening.

Basic Information

Product Name	4-Chloro-2-Fluoroiodobenzene
CAS No.	6797-79-1
Molecular Formula	C6H3ClFI
Molecular Weight	256.44 g/mol
Synonyms	1-Chloro-4-fluoro-2-iodobenzene; 2-Fluoro-4-chloroiodobenzene; 4-Chloro-2-fluoro-1-iodobenzene; Benzene, 1-chloro-4-fluoro-2-iodo-; 4-Chloro-2-fluorophenyl iodide
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoroiodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.