Description

6,18-Dioxo-6,18-Epoxy-6,7-Secokaura-16-Ene-7-Oic Acid is a specialized diterpenoid derivative with a complex, functionalized kaurane skeleton. This compound serves as a critical advanced intermediate in the synthesis of novel bioactive molecules, offering unique structural features for chemical modification. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing new therapeutic agents and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel diterpenoid-based drug candidates with potential anti-inflammatory or anticancer activity.
• Medicinal Chemistry Research: Used in lead optimization and scaffold-hopping studies to explore new chemical space and biological targets.
• Natural Product Analog Synthesis: Serves as a starting material for creating synthetic analogs of bioactive natural kaurane diterpenoids.
• Chemical Biology Probes: Functionalized to create tool compounds for studying biological pathways and enzyme interactions.
• Academic Research: Employed in university and institutional labs for studies in organic synthesis methodology and natural product chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value, low-volume specialty chemicals.

Basic Information

Product Name	6,18-Dioxo-6,18-Epoxy-6,7-Secokaura-16-Ene-7-Oic Acid
CAS No.	6750-12-5
Molecular Formula	C20H24O5
Molecular Weight	344.40 g/mol
Synonyms	6,18-Epoxy-6,7-secokaur-16-ene-7,6,18-trione; 7-Carboxy-6,18-epoxy-6,7-secokaur-16-ene-6,18-dione; Kaur-16-en-6,18-epoxy-7-oic acid, 6,18-dioxo-6,7-seco-; 6,7-Secokaur-16-ene-7-oic acid, 6,18-dioxo-6,18-epoxy-; Ent-6,18-Epoxy-6,7-secokaur-16-ene-7,6,18-trione; (4bR,8aS,10aS)-10a-Methyl-5-methylidene-2,9-dioxo-3,4,4b,5,6,7,8,8a,9,10-decahydro-1H-phenanthrene-4a-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6,18-Dioxo-6,18-Epoxy-6,7-Secokaura-16-Ene-7-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.