Description

1H-Benzimidazole,4-Methyl-2-(Trifluoromethyl)-(9Ci) is a specialized trifluoromethylated benzimidazole derivative, a high-value heterocyclic building block prized for its unique electronic and steric properties. This compound is critical for advanced research and development in medicinal chemistry and material science, where the introduction of a trifluoromethyl group can dramatically alter a molecule's metabolic stability, lipophilicity, and binding affinity. It is primarily sought after by pharmaceutical R&D teams and agrochemical innovators for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced fungicides, herbicides, and pesticides, where the benzimidazole core and fluorine atoms contribute to biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up development.

Basic Information

Product Name	1H-Benzimidazole,4-Methyl-2-(Trifluoromethyl)-(9Ci)
CAS No.	6742-83-2
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	4-Methyl-2-(trifluoromethyl)-1H-benzimidazole; 2-(Trifluoromethyl)-4-methylbenzimidazole; 4-Methyl-2-trifluoromethylbenzimidazole; 1H-Benzimidazole, 4-methyl-2-(trifluoromethyl)-; 4-Methyl-2-(trifluoromethyl)benzimidazole; 6742-83-2; 4-Methyl-2-trifluoromethyl-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole,4-Methyl-2-(Trifluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.