Description

3,3,6,6-Tetramethyl-1,4-Dioxane-2,5-Dione is a high-purity cyclic diester, also known as the dimer of pivalic acid. This compound serves as a versatile and valuable building block in advanced organic synthesis, prized for its unique steric properties and reactivity. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors who require high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing sterically hindered ester and amide functionalities.
• Polymer Chemistry: Serves as a monomer or co-monomer for producing specialty polyesters and polycarbonates with enhanced thermal stability and specific degradation profiles.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides where its bulky structure can impart favorable biological activity and stability.
• Ligand and Catalyst Preparation: Employed as a starting material for synthesizing chiral auxiliaries and complex ligands used in asymmetric catalysis.
• Fine Chemical Production: A crucial intermediate for creating complex esters, lactones, and other high-value specialty chemicals.
• Material Science Research: Investigated for use in developing novel biodegradable materials and controlled-release matrices.

Basic Information

Item	Detail
Product Name	3,3,6,6-Tetramethyl-1,4-Dioxane-2,5-Dione
CAS No.	6713-72-0
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	Diketene Dimer of Pivalic Acid; Pivalic Anhydride Dimer; 2,5-Dioxo-3,3,6,6-tetramethyl-1,4-dioxane; Tetramethyl-1,4-dioxane-2,5-dione; TM-DOD; Pivalolactone Dimer; 3,3,6,6-Tetramethyl-1,4-dioxacyclohexane-2,5-dione
EINECS	229-761-5

Quality Control

Our 3,3,6,6-Tetramethyl-1,4-Dioxane-2,5-Dione is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.