Description

3-Methoxy-4-[(trimethylsilyl)oxy]benzaldehyde is a versatile organosilicon-protected aldehyde derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in the silyl-protected phenolic hydroxyl group, which provides enhanced stability and selective reactivity for complex multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for constructing complex molecules where controlled functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing protected catechol or vanillin-like motifs.
• Fine Chemical Synthesis: Used in the preparation of specialty chemicals, flavors, fragrances, and advanced materials requiring selective aldehyde chemistry.
• Agrochemical Research: Intermediate in the development of novel pesticides and herbicides where the protected phenolic group is advantageous.
• Polymer Chemistry: Monomer or modifier in the synthesis of specialty polymers and resins with tailored properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic additions, and as a precursor for heterocycle formation in academic and industrial R&D.
• Ligand and Catalyst Development: Starting material for synthesizing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Methoxy-4-[(trimethylsilyl)oxy]benzaldehyde
CAS No.	6689-43-6
Molecular Formula	C11H16O3Si
Molecular Weight	224.33 g/mol
Synonyms	4-(Trimethylsilyloxy)-3-methoxybenzaldehyde; 3-Methoxy-4-(trimethylsiloxy)benzaldehyde; Vanillin trimethylsilyl ether; 4-Formyl-2-methoxyphenyl trimethylsilyl ether; Benzaldehyde, 3-methoxy-4-[(trimethylsilyl)oxy]-; TMS-Protected Vanillin; O-Trimethylsilylvanillin; 4-(Trimethylsilyl)oxy-3-methoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-[(trimethylsilyl)oxy]benzaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.