Description

4-Bromo-3-Chlorotoluene is a halogenated aromatic compound of significant industrial importance, serving as a versatile intermediate in advanced organic synthesis. Its value lies in the strategic positioning of bromine and chlorine substituents on the toluene ring, which enables selective functionalization for building complex molecular architectures. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the bromo-chloro-toluene structure imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating halogenated derivatives used in colorants and functional dyes.
• Custom Chemical Synthesis: Provides a versatile substrate for further bromination, chlorination, or metal-halogen exchange reactions in contract research and manufacturing.

Basic Information

Product Name	4-Bromo-3-Chlorotoluene
CAS No.	6627-51-6
Molecular Formula	C7H6BrCl
Molecular Weight	205.48 g/mol
Synonyms	1-Bromo-2-chloro-4-methylbenzene; 3-Chloro-4-bromotoluene; Toluene, 4-bromo-3-chloro-; 4-Methyl-1-bromo-2-chlorobenzene; 2-Chloro-4-bromotoluene; 4-Bromo-3-chloro-1-methylbenzene; 4-Bromo-3-chloromethylbenzene
EINECS	229-589-6

Quality Control

Our 4-Bromo-3-Chlorotoluene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical properties to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.