Description

1-(4-Fluoro-Phenyl)-2-Pyridin-4-Yl-Ethanone is a high-purity organic building block featuring both a fluorinated phenyl ring and a pyridine moiety, making it a versatile intermediate for advanced synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorinated and heterocyclic motifs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or fluorophores for OLEDs.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags that leverage the pyridine group for metal coordination or hydrogen bonding.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-2-Pyridin-4-Yl-Ethanone
CAS No.	6576-05-2
Molecular Formula	C₁₃H₁₀FNO
Molecular Weight	215.22 g/mol
Synonyms	4'-Fluoro-4-pyridylacetophenone; 1-(4-Fluorophenyl)-2-(4-pyridinyl)ethanone; 4-Pyridin-4-yl-4'-fluoroacetophenone; 4-(4-Fluorobenzoyl)methylpyridine; 2-(4-Pyridyl)-1-(4-fluorophenyl)ethanone; p-Fluoro-α-pyrid-4-ylacetophenone; 6576-05-2; 4-Fluorophenyl 4-pyridyl ketone (common name)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-2-Pyridin-4-Yl-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We support compliance with ICH guidelines and can tailor quality standards to meet specific customer requirements for research or cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.