Description

2-Chloro-6-Nitrobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a chloro substituent, makes it a key intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with heterocyclic or complex aromatic backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its substituted benzene ring serves as a core structural element.
• Dye and Pigment Manufacturing: Acts as a starting material for synthesizing specialized azo dyes and organic pigments due to its reactive nitro and cyano groups.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination for creating biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2-Chloro-6-Nitrobenzonitrile
CAS No.	6575-07-1
Molecular Formula	C7H3ClN2O2
Molecular Weight	182.56 g/mol
Synonyms	2-Chloro-6-nitrobenzonitrile; 6-Chloro-2-nitrobenzonitrile; Benzonitrile, 2-chloro-6-nitro-; 2-Nitro-6-chlorobenzonitrile; NSC 403107; 2-Chloro-6-nitro-benzonitrile; 6-Nitro-2-chlorobenzonitrile; o-Chloro-m-nitrobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Nitrobenzonitrile is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and specific test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.