Description

1,2,4-Trichloro-5-Ethynyl-Benzene is a high-value halogenated aromatic building block featuring a reactive ethynyl group. This compound is critical for the synthesis of complex organic molecules, particularly in advanced material science and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a halogenated aromatic core with a functional handle for further coupling reactions (e.g., Sonogashira coupling).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, where the trichloro-phenyl moiety can contribute to biological activity and stability.
• Material Science Research: Acts as a monomer or building block for developing advanced polymers, liquid crystals, or organic electronic materials due to its conjugated ethynyl group.
• Organic Synthesis & Catalysis: Employed in academic and industrial laboratories as a specialized reagent for constructing complex organic molecules, often used in cross-coupling reactions and as a ligand precursor.
• Chemical Intermediate: Functions as a versatile intermediate for further functionalization to produce dyes, pigments, and other fine chemicals.

Basic Information

Product Name	1,2,4-Trichloro-5-Ethynyl-Benzene
CAS No.	6546-87-8
Molecular Formula	C8H3Cl3
Molecular Weight	221.47 g/mol
Synonyms	5-Ethynyl-1,2,4-trichlorobenzene; 1,2,4-Trichloro-5-ethynylbenzene; 2,4,5-Trichlorophenylethyne; (2,4,5-Trichlorophenyl)acetylene; Benzene, 1,2,4-trichloro-5-ethynyl-
EINECS	Contact for details

Quality Control

Our 1,2,4-Trichloro-5-Ethynyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.