Description

Norgestrel CAS NO 6533-00-2 is a synthetic progestogen, a key active pharmaceutical ingredient (API) belonging to the 19-nortestosterone class. It is a critical component in hormonal contraceptive formulations and other therapeutic applications, valued for its potent progestational activity and stability. This high-purity compound is essential for pharmaceutical manufacturers, research institutions, and developers of hormone replacement therapies and birth control products.

Application

• Active Pharmaceutical Ingredient (API) in oral contraceptive pills, often combined with an estrogen like ethinyl estradiol.
• Hormone Replacement Therapy (HRT) for managing symptoms of menopause and other hormonal imbalances.
• Progestogen-Only Contraceptives, including mini-pills and emergency contraceptive formulations.
• Pharmaceutical Research & Development for studying progestogen receptor activity and developing new therapeutic agents.
• Reference Standard for analytical testing, quality control, and method validation in pharmaceutical laboratories.
• Veterinary Pharmaceuticals for hormonal regulation and reproductive management in animals.

Basic Information

Product Name	Norgestrel
CAS No.	6533-00-2
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	DL-Norgestrel; (±)-Norgestrel; 13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one; 17α-Ethynyl-18-methyl-19-nortestosterone; Wyeth 3700; d,l-Norgestrel; NSC-72423; Ovrette (brand name component); Levonorgestrel impurity B (racemic mixture)
EINECS	229-447-0

Quality Control

Our Norgestrel is manufactured under strict quality management systems. It is tested to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for identity, purity, assay, and related substances. We ensure traceability, consistency, and regulatory compliance for all our shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual unspecified impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	-30.0° to -35.0° (c=1 in chloroform)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.