Description

1-[(4-Methylphenyl)Sulfonyl]Pyrrolidine is a specialized sulfonamide derivative, a high-value intermediate in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific sulfonyl-pyrrolidine motifs into target structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing sulfonamide pharmacophores.
• Medicinal Chemistry Research: Used in high-throughput screening and the development of novel drug candidates targeting various enzymes and receptors.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and insecticides that utilize sulfonyl chemistry.
• Material Science: Potential monomer or additive in the development of specialty polymers with tailored properties.
• Chemical Biology Probes: Serves as a precursor for designing molecular probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1-[(4-Methylphenyl)Sulfonyl]Pyrrolidine
CAS No.	6435-78-5
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	1-(p-Toluenesulfonyl)pyrrolidine; N-(p-Tolylsulfonyl)pyrrolidine; 1-Tosylpyrrolidine; N-Tosylpyrrolidine; Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-; 1-(4-Methylbenzenesulfonyl)pyrrolidine; p-Toluenesulfonpyrrolidine; Tosylpyrrolidine
EINECS	Contact for details

Quality Control

Our 1-[(4-Methylphenyl)Sulfonyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.