Description

2-Chloro-5-Nitrobenzaldehyde is a versatile aromatic aldehyde building block characterized by its chloro and nitro substituents, which impart significant reactivity for further chemical transformations. This compound matters as a key intermediate in the synthesis of complex molecules, offering a strategic handle for introducing functional diversity into target structures. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzodiazepine or other fused heterocyclic structures.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where its reactive aldehyde group facilitates the construction of complex bioactive molecules.
• Dye and Pigment Production: Serves as a starting material for synthesizing azo dyes and other organic colorants, leveraging the nitro group for chromophore development.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to create novel chelating ligands for catalysis and material science applications.
• Cross-Coupling Reactions: The aldehyde and halogen functionalities make it a suitable substrate for palladium-catalyzed cross-coupling reactions like Suzuki or Heck reactions.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and synthesizing libraries of compounds for screening.

Basic Information

Product Name	2-Chloro-5-Nitrobenzaldehyde
CAS No.	6361-21-3
Molecular Formula	C7H4ClNO3
Molecular Weight	185.56 g/mol
Synonyms	5-Nitro-2-chlorobenzaldehyde; 2-Chloro-5-nitrobenzenecarboxaldehyde; 2-Chloro-5-nitrobenzene-1-carbaldehyde; 2-Chloro-5-nitro-benzaldehyde; Benzaldehyde, 2-chloro-5-nitro-; NSC 403119; 2-Chloro-5-nitrobenzaldehyd; 5-Nitro-o-chlorobenzaldehyde
EINECS	228-877-9

Quality Control

Our 2-Chloro-5-Nitrobenzaldehyde is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	73 - 77 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.