Description

5-Chloro-2-Methoxyacetophenone is a versatile aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both chloro and methoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it serves as a precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various active pharmaceutical ingredients (APIs), particularly those with aryl ketone or benzofuran scaffolds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents that require a halogenated methoxyacetophenone core structure.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or host materials in the manufacture of OLED displays and lighting.
• Liquid Crystal & Dye Intermediates: Employed in the synthesis of advanced materials for electronic displays and high-performance pigments.
• Flavor & Fragrance Chemistry: Acts as a building block for synthesizing specific aromatic compounds used in specialty fragrance formulations.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	5-Chloro-2-Methoxyacetophenone
CAS No.	6342-64-9
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	1-(5-Chloro-2-methoxyphenyl)ethanone; 2'-Methoxy-5'-chloroacetophenone; 5-Chloro-2'-methoxyacetophenone; 5-Chloro-o-methoxyacetophenone; 2-Acetyl-4-chloroanisole; 4-Chloro-2-acetylanisole; Ethanone, 1-(5-chloro-2-methoxyphenyl)-
EINECS	228-746-8

Quality Control

Our 5-Chloro-2-Methoxyacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.