Description

Diethyl Formamidomalonate is a versatile and high-purity organic building block, essential for the synthesis of complex heterocyclic compounds and fine chemicals. Its primary value lies in its role as a key precursor for the preparation of pharmaceuticals, agrochemicals, and advanced materials, enabling efficient multi-step synthetic routes. This product is critically needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyrimidine and purine derivatives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a key reagent for manufacturing dyes, pigments, and other performance chemicals.
• Academic & Industrial Research: Employed in organic synthesis research for developing new methodologies and novel compounds.
• Peptidomimetics & Amino Acid Derivatives: Acts as a protected glycine equivalent for the preparation of modified amino acids and peptide analogs.
• Heterocyclic Chemistry: A fundamental building block for constructing pyrimidines, uracils, and other nitrogen-containing heterocycles.

Basic Information

Product Name	Diethyl Formamidomalonate
CAS No.	6326-44-9
Molecular Formula	C8H13NO5
Molecular Weight	203.19 g/mol
Synonyms	Diethyl (formylamino)malonate; Formamidomalonic Acid Diethyl Ester; Diethyl N-Formylaminomalonate; N-Formylaminomalonic Acid Diethyl Ester; Ethyl Formamidomalonate; Diethyl (Formamido)malonate; Malonic acid, (formylamino)-, diethyl ester; NSC 403697
EINECS	228-690-3

Quality Control

Our Diethyl Formamidomalonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	74 - 78 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.