Description

1-Cyclohexyl-5-Oxo-Pyrrolidine-3-Carboxylic Acid is a high-purity, versatile pyrrolidinone derivative used as a critical building block in advanced organic synthesis. This compound is valued for its unique structural features, which enable the construction of complex molecules with specific stereochemistry and functional groups. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticide and herbicide intermediates, leveraging its cyclic structure for bioactive molecule design.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and protease inhibitors due to its constrained pyrrolidinone backbone.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high-purity intermediates.

Basic Information

Product Name	1-Cyclohexyl-5-Oxo-Pyrrolidine-3-Carboxylic Acid
CAS No.	6304-56-9
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	3-Carboxy-1-cyclohexyl-2-pyrrolidinone; 1-Cyclohexyl-5-oxopyrrolidine-3-carboxylic acid; 1-Cyclohexyl-2-oxopyrrolidine-4-carboxylic acid; 4-Carboxy-1-cyclohexyl-2-pyrrolidinone; NSC 163063; 3-Pyrrolidinecarboxylic acid, 1-cyclohexyl-5-oxo-; 1-Cyclohexyl-5-oxo-3-pyrrolidinecarboxylic acid; Cyclohexylsuccinimide-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-5-Oxo-Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the exacting standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.