Description

2-Hydroxy-1,7,7-Trimethylbicyclo[2.2.1]heptane-2-carbonitrile is a high-purity, specialized bicyclic nitrile derivative with a hydroxyl functional group. This compound is valued for its unique sterically hindered structure, which makes it a versatile chiral building block and intermediate in advanced organic synthesis. It is primarily sought by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its bicyclic framework for biological activity.
• Fine Chemical Production: Acts as a building block for fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological studies and catalysis research as a model substrate for testing new synthetic routes, such as asymmetric hydroxylation or cyanation reactions.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties due to its rigid bicyclic structure.

Basic Information

Product Name	2-Hydroxy-1,7,7-Trimethylbicyclo[2.2.1]heptane-2-carbonitrile
CAS No.	6246-40-8
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	2-Cyano-2-hydroxybornane; 2-Hydroxybornane-2-carbonitrile; 2-Hydroxy-2-bornanecarbonitrile; (1R,2S,4R)-2-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane-2-carbonitrile; (+)-2-Hydroxybornane-2-carbonitrile; Bicyclo[2.2.1]heptane-2-carbonitrile, 2-hydroxy-1,7,7-trimethyl-; Bornane-2-carbonitrile, 2-hydroxy-
EINECS	228-387-9

Quality Control

Our 2-Hydroxy-1,7,7-Trimethylbicyclo[2.2.1]heptane-2-carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets exacting R&D and production standards. A detailed Certificate of Analysis (COA) with full specifications and chromatographic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.