Description

(Triphenylsilyl)Acetylene is a high-purity organosilicon building block featuring a reactive terminal alkyne group protected by a robust triphenylsilyl moiety. This compound is essential for advanced organic synthesis, particularly in cross-coupling and cycloaddition reactions, where it serves as a versatile and stable acetylene synthon. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates via Sonogashira and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides that incorporate acetylene-linked structural motifs.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalizing agent in the creation of specialty polymers, dendrimers, and organic electronic materials.
• Organic Synthesis Reagent: Employed in Huisgen cycloaddition (click chemistry) to create triazole linkages and in the preparation of conjugated molecular systems for optoelectronics.
• Chemical Research & Development: A valuable tool in academic and industrial R&D labs for methodology development and exploring new reaction pathways involving protected alkynes.

Basic Information

Product Name	(Triphenylsilyl)Acetylene
CAS No.	6229-00-1
Molecular Formula	C20H16Si
Molecular Weight	284.43 g/mol
Synonyms	Ethynyltriphenylsilane; Triphenyl(ethynyl)silane; Triphenylsilylacetylene; Silane, ethynyltriphenyl-; (Ethynyl)triphenylsilane; TPS-acetylene; TPSA
EINECS	228-324-8

Quality Control

Our (Triphenylsilyl)Acetylene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure a typical purity of ≥98% and conformity with internal specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent performance for your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.