Description

1-o-Methyl-2-O,3-O,4-o-Triacetyl-5,6-Didehydro-6-Deoxy-α-D-Glucopyranose is a key protected monosaccharide derivative, serving as a versatile chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold for constructing complex bioactive molecules with precise stereochemistry. This intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of nucleoside analogs, glycosidase inhibitors, and other specialized carbohydrate-based therapeutics.

Application

• Pharmaceutical Intermediate: Critical chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with antiviral or anticancer activity.
• Glycochemistry Research: Used as a protected precursor for constructing complex oligosaccharides, glycoconjugates, and glycomimetics.
• Enzyme Inhibitor Development: Serves as a core structure for designing and testing glycosidase and glycosyltransferase inhibitors.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of high-value specialty chemicals requiring specific sugar-derived chirality.
• Process Chemistry: Utilized in route development and scale-up for active pharmaceutical ingredients (APIs) where this specific protected sugar motif is required.

Basic Information

Item	Details
Product Name	1-o-Methyl-2-O,3-O,4-o-Triacetyl-5,6-Didehydro-6-Deoxy-α-D-Glucopyranose
CAS No.	6217-21-6
Molecular Formula	C13H18O8
Molecular Weight	302.28 g/mol
Synonyms	1-O-Methyl-2,3,4-tri-O-acetyl-5,6-didehydro-6-deoxy-α-D-glucopyranose; 6-Deoxy-1-O-methyl-2,3,4-tri-O-acetyl-α-D-xylo-hex-5-enopyranose; Methyl 2,3,4-tri-O-acetyl-6-deoxy-α-D-xylo-hex-5-enopyranoside; 5,6-Didehydro-6-deoxy-1-O-methyl-2,3,4-tri-O-acetyl-α-D-glucopyranose; 1-Methyl 2,3,4-triacetate of 5,6-didehydro-6-deoxy-α-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 1-o-Methyl-2-O,3-O,4-o-Triacetyl-5,6-Didehydro-6-Deoxy-α-D-Glucopyranose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.