Description

Heliotrine, 4-Oxide is a pyrrolizidine alkaloid derivative, a compound of significant interest in specialized chemical research and development. Its structure makes it a valuable reference standard and intermediate for investigating alkaloid chemistry and toxicology. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require high-purity, well-characterized chemical entities.

Application

• Pharmaceutical Research: Serves as a critical reference standard and analytical marker in the study of pyrrolizidine alkaloid (PA) toxicity, metabolism, and detoxification pathways.
• Toxicology Studies: Used as a certified standard in analytical methods (HPLC, LC-MS) for the detection and quantification of hepatotoxic alkaloids in herbal products, food, and supplements.
• Biochemical Research: Employed as a precursor or intermediate in the synthesis of more complex alkaloid structures for biological activity screening.
• Agrochemical Development: Investigated for its potential as a lead compound or biosynthetic intermediate in the development of novel plant-derived agents.
• Quality Control Laboratories: Essential for calibrating equipment and validating analytical procedures in labs that monitor PA contamination to ensure consumer safety.
• Academic Research: Used in universities and research institutes for studies in natural product chemistry, phytochemistry, and chemical ecology.

Basic Information

Product Name	Heliotrine, 4-Oxide
CAS No.	6209-65-0
Molecular Formula	C16H27NO6
Molecular Weight	329.39 g/mol
Synonyms	Heliotrine N-Oxide; Heliotrine 4-Oxide; Heliotrine Oxide; 3'-Hydroxy-1,2-dehydroheliotridan-7-one 4-Oxide; (15,7aR)-1-(2-Methylbutyryloxy)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl 4-oxide; Heliotrine-4α-oxide; Lasiocarpine N-Oxide isomer; Pyrrolizidine alkaloid oxide
EINECS	Contact for details

Quality Control

Our Heliotrine, 4-Oxide is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and analytical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for reference materials, ensuring reliable and reproducible results for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.