Description

cis-2-(Bromomethyl)-1,3-Dioxolane-4-Methanol is a versatile brominated acetal derivative, primarily valued as a key chiral building block and reactive intermediate in advanced organic synthesis. Its structure, featuring both a bromomethyl group and a protected diol moiety, makes it an essential precursor for constructing complex molecules with high stereochemical control. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and fine chemical industries, where it is used to develop active pharmaceutical ingredients (APIs), nucleoside analogs, and specialty polymers.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Fine Chemical Synthesis: Used in the preparation of complex natural products, ligands for catalysis, and other high-value specialty chemicals.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating novel polymers with specific properties.
• Agrochemical Research: Employed in the development of new, more effective pesticide and herbicide candidates.
• Material Science: Acts as a precursor for surface modifiers and advanced materials requiring specific functional groups.
• Academic & R&D: A valuable reagent in laboratory-scale research for methodological development and exploring new chemical reactions.

Basic Information

Product Name	cis-2-(Bromomethyl)-1,3-Dioxolane-4-Methanol
CAS No.	6204-42-8
Molecular Formula	C5H9BrO3
Molecular Weight	197.03 g/mol
Synonyms	4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane-4-methanol; (4R-cis)-4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane-4-methanol; 2-(Bromomethyl)-2-methyl-1,3-dioxolane-4-methanol; 1,3-Dioxolane-4-methanol, 2-(bromomethyl)-; Bromoacetaldehyde Acetal of Glycerol; Glycerol Bromoacetal; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of cis-2-(Bromomethyl)-1,3-Dioxolane-4-Methanol is produced and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric purity (where applicable), and impurity profiles. Our quality systems are designed to support cGMP manufacturing for pharmaceutical intermediates, ensuring full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.